Dr. Rajarajan published many research articles in the Embryology and Stem cells field in International Journals with high Impact Factors.
Sturzu AC, Rajarajan Kuppusamy, Passer D, Plonowska K, Riley A, Tan TC, Sharma A, Xu AF, Engels MC, Feistritzer R, Li G, Selig MK, Geissler R, Robertson KD, Scherrer-Crosbie M, Domian IJ, Wu SM. Fetal Mammalian Heart Generates a Robust Compensatory Response to Cell Loss. Circulation 2015 ;132:109-121.(Blastocyst-ES Cell Injection/Chimeric embryo production work).
K. Rajarajan, B.S. Rao, R. Vagdevi, G. Tamilmani, G. Arunakumai, M. Sreenu, D.Amarnath, B.R. Naik and V.H. Rao. Effect of various growth factors on the in vitro development of goat preantral follicles. Small Ruminant Research 63 (2006) 204–212.
Marc C. Engels, Kuppusamy Rajarajan, Ulrik B. Nielsen, Martin J. Schalij, Daniel A. Pijnappels, Sean M. Wu. IGF promotes cardiac lineage induction by selective expansion of cardiogenic mesoderm in vitro. Stem Cells 2014. Jun;32(6):1493-502.
Rajarajan, K., Engels, M. C. and Wu, S. M. 2012. Reprogramming of Mouse, Rat, Pig, and Human Fibroblasts into iPS Cells. Current Protocols in Molecular Biology. 97:23.15.1–23.15.32.
Rajarajan.K, Rao B.S, Tamilmani G, Arunakumari G, Naik R.B and Rao V.H. In vitro culture of Pre-antral follicles from goat ovaries. (2002) 9th International Congress on Biotechnology in Animal reproduction, Madras Veterinary College, Chennai, India. PS-
I/29, Page: 227.
Bharati B, Rao B.S, Rajarajan.K, Naik R.B, Arunakumari G and Rao V.H. Parthinogenetic activation of in vitro matured goat oocytes. (2002) 9th International Congress on Biotechnology in Animal reproduction, Madras Veterinary College, Chennai, India. PS-I/30,
Page: 227.
Kuppusamy Rajarajan, BeccaFeistritzer, Marc C. Engels, Anthony Sturzu, Kenta Nakamura, Hinson John T, Xiaojing Huang, Guang Li, Wenpo Chuang, Karolina Plonowska, Ken-ichi Hirano and Sean M. Wu. HTS drug Screening in Human Neutral Lipid Storage Disease iPS cells Identifies Modulators of Intracellular Lipid Metabolism That Reduce Disease Phenotype In Vitro. Nature Biotechnology. (Manuscript Under Revision).
Rajarajan K, Saikumar G and Sharma G.Taru. Expression of developmentally important genes involved in energy metabolism in Buffalo (Bubalus bubalis) oocytes and preimplantation embryos produced in vitro. (2009). Germ cell development-function &
ISSRF 19th Annual meeting, IISC, Bangalore, India.
M. Karunakaran, Mohan Mondal, K. Rajarajan, H.D. Karmakar, B.P. Bhat, JitumoniDas, Bhaskar Bora, K.K. Baruah, C. Rajkhowa. Early puberty in local Naga boar ofIndia: assessment through epididymal spermiogram and in vivo pregnancy. Animal
Reproduction Science, 111, 1 (2009) 112-119.
S.Eswari, K.Rajarajan, G. Sai kumar and G. Taru Sharma. Effect of supplementation of Leukemia Inhibitory Factor on in vitro development of buffalo embryos. Tamil Nadu Journal of Veterinary and Animal Sciences, 6(6) 2010, 255-261.
Hinson JT, Chopra A, Lowe A, Sheng CC, Gupta RM, Kuppusamy Rajarajan, O'Sullivan J, Rowe G, Wakimoto H, Gorham J, Zhang K, Musunuru K, Gerszten RE, Wu SM, Chen CS, Seidman JG, Seidman CE. Integrative Analysis of PRKAG2 Cardiomyopathy iPS and Microtissue Models Identifies AMPK as a Regulator of Metabolism, Survival, and Fibrosis. Cell Reports. 2016 Dec 20;17(12):3292-3304.
Wenpo Chuang, Arun Sharma, Praveen Shukla, Guang Li, Moritz Mall, Kuppusamy Rajarajan, Oscar J.Abilez, Ryoko Hamaguchi, Joseph C.Wu, Marius Wernig & Sean M.Wu. Partial Reprogramming of Pluripotent Stem Cell-Derived Cardiomyocytes into Neurons. Scientific Reports, Nature group of publications. 7, 44840; 2017.
Guang Li, Karolina Plonowska, Kuppusamy Rajarajan, Anthony Sturzu, and Sean Wu. Identification of Cardiovascular Lineage Descendants at Single Cell Resolution. Development 2015, 142, 1-12.
Sharma A*, Li G*, Rajarajan Kuppusamy*, Hamaguchi R, Burridge PW, Wu SM. Derivation of highly purified cardiomyocytes from human induced pluripotent stem cells using small molecule-modulated differentiation and subsequent glucose starvation. J Vis Exp. 2015 Mar 18 ;( 97). (*Equal Contribution).
Stefanie A. Doppler, Astrid Werner, Melanie Barz, Harald Lahm, Marcus-André Deutsch, Martina Dreßen, Matthias Schiemann, Serge Gregoire, Kuppusamy Rajarajan, Sean M. Wu, Rüdiger Lange, Markus Krane. Myeloid Zinc Finger 1 (Mzf1) Differentially Modulates Murine Cardiogenesis by Interacting With an Nkx2.5 Cardiac Enhancer. PLoS One. 2014 Dec 1:9(12):e113775.
Arun Sharma, Caleb Marceau. Karim I. Sallam, Rajarajan Kuppusamy, Glared Churko, Nicholas M. Mordwinkin, Vvenpo Lnuang, Ping Liang, Elena Matsa, Paul W. Burridge, Frances Barron, Kristy Red-Horse, Jan E. Carette, Sean M. Wu and Joseph C. W u. Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes as an In Vitro Model for Coxsackievirus B3-Induced Myocarditis and Antiviral Drug Screening Platform. Circulation Research. 2014 Aug 29;115(6):556-66
M.C. Engels, K. Rajarajan, R. Feistritzer, A. Sharma, U.B. Nielsen, M.J. Schalij, A.A.F. De Vries, D.A. Pijnappels and S.M. Wu. IGF promotes cardiac lineage induction by selective expansion of cardiogenic mesoderm in vitro. Eur Heart J (2013) 34 (suppl 1): doi:10.1093/eurheartj/eht310.P5037.
J.X. Chen, M. Krane, M. A. Deutsch, L. Wang, M. Rav-Acha, S. Gregoire, M. C. Engels, K. Rajarajan, R. Karra, E. D. Abel, J. C. Wu, D. Milan, S.M. Wu. Inefficient reprogramming of fibroblasts into cardiomyocytes using Gata4, Mef2c, Tbx5. Circulation Research. 2012 Jun 22; 111(1):50-5.
Lakshmanan Jeyabal, Debdatta Ray, Sundaram Sureshkannan, Kumaresan Nagarajan, Sivam Visnuvinayagam, Srikanth Ghosh, Partha Sarathi Banerjee, Shanmugam Chandra Sekar, Madiajagan Bagath, Krishanan Padmanath, Kuppusamy Rajarajan and Pentela Ravikumar. First Report of Moraxella Bovis Infection in Indian Cattle. Advances in Animal and Veterinary Sciences 2013.